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For research purposes only — not for human consumption. For laboratory and educational reference.
MOTS-c
Longevity

MOTS-c

MOTS-c is a mitochondrial-derived peptide encoded within mitochondrial DNA and recognized for its role in cellular energy regulation and metabolic stress signaling. It has been studied extensively in longevity and metabolic research for its relationship to mitochondrial homeostasis, insulin sensitivity, exercise-associated signaling, and adaptive cellular stress responses across preclinical models.

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1627580-64-6
CAS
2174.64 g/mol
Molecular weight
3mL
Vial

What is MOTS-c?

Longevity · 10mg, 40mg · 3mL

MOTS-c is a mitochondrial-derived peptide encoded within mitochondrial DNA and recognized for its role in cellular energy regulation and metabolic stress signaling. It has been studied extensively in longevity and metabolic research for its relationship to mitochondrial homeostasis, insulin sensitivity, exercise-associated signaling, and adaptive cellular stress responses across preclinical models. Unlike most signaling peptides encoded within nuclear DNA, MOTS-c originates directly from the mitochondrial genome and functions as a mitochondrial-to-nuclear communication peptide. Lyophilized powder, 3mL vial. Sold at 10mg and 40mg per vial. For research use only.

Sequence MRWQEMGYIFYPRKLR. 16-aa mitochondrial-derived peptide.

Compound Information

Technical specifications

Molecular Profile

What Is MOTS-c?

Type Peptide
CAS Number 1627580-64-6
Molecular Weight 2174.64 g/mol
Amino Acids 16 amino acids
Formula C101H152N28O22S2
PubChem Database
Storage Requirements

Stability Information

  • Lyophilized
  • Protect from light
  • For research use only
  • Lyophilized
    -20°C 24 months (unopened)
  • Reconstituted
    2–8°C Up to 30 days
  • Working solution
    2–8°C Use within 7 days

Product specifications

Technical details

Technical specifications
CAS number
1627580-64-6
Molecular formula
C101H152N28O22S2
Molecular weight
2174.64 g/mol g/mol
Type
Peptide
Residues / units
16 amino acids
Vial size
3mL
Molecular weight
2174.64 g/mol — Registry verified

Storage & Handling

Storage conditions for unopened vials

LYOPHILIZED
-20°C

Long-term storage. Protect from moisture and light.

RECONSTITUTED
2–8°C

Refrigerate after reconstitution. Do not freeze reconstituted solution unless validated for your protocol.

SHIPPING
Ambient

Lyophilized peptides ship at ambient temperature under normal conditions.

WARNINGS
  • For research use only — not for human or veterinary consumption.
  • Handle with appropriate PPE in a controlled laboratory environment.
  • Confirm form, salt, and concentration against your supplier CoA before use.

Sources & References

Peer-reviewed research

Database PubChem CID 146675088 View Source

MOTS-c is a mitochondrial-derived peptide encoded within mitochondrial DNA and recognized for its role in cellular energy regulation and metabolic stress signaling. It has been studied extensively in longevity and metabolic research for its relationship to mitochondrial homeostasis, insulin sensitivity, exercise-associated signaling, and adaptive cellular stress responses across preclinical models. Unlike most signaling peptides encoded within nuclear DNA, MOTS-c originates directly from the mitochondrial genome and functions as a mitochondrial-to-nuclear communication peptide. Lyophilized powder, 3mL vial. Sold at 10mg and 40mg per vial. For research use only.

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