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For research purposes only — not for human consumption. For laboratory and educational reference.

TB-500

TB-500 is a synthetic peptide derived from the active region of thymosin beta-4, a naturally occurring actin-binding protein involved in cellular migration and tissue organization. It has been studied extensively in regenerative research for its relationship to connective tissue signaling, angiogenesis, wound modeling, and cellular repair pathways across musculoskeletal and soft-tissue systems.

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77591-33-4
CAS
4963.44 g/mol
Molecular weight
3mL
Vial

What is TB-500?

Regenerative · 10mg · 3mL

TB-500 is a synthetic peptide derived from the active region of thymosin beta-4, a naturally occurring actin-binding protein involved in cellular migration and tissue organization. It has been studied extensively in regenerative research for its relationship to connective tissue signaling, angiogenesis, wound modeling, and cellular repair pathways across musculoskeletal and soft-tissue systems. Its sequence retains the biologically active region associated with actin regulation while functioning independently from the full thymosin beta-4 protein structure. Lyophilized powder, 3mL vial. Sold at 10mg per vial. For research use only.

Full Thymosin β-4 (43-aa) acetylated. Some 'TB-500' products are actually the Ac-LKKTETQ heptapeptide fragment (~889 g/mol) — CONFIRM with COA.

Compound Information

Technical specifications

Molecular Profile

What Is TB-500?

Type Peptide
CAS Number 77591-33-4
Molecular Weight 4963.44 g/mol
Amino Acids 43 amino acids
Formula C212H350N56O78S
Storage Requirements

Stability Information

  • Lyophilized
  • Protect from light
  • For research use only
  • Lyophilized
    -20°C 24 months (unopened)
  • Reconstituted
    2–8°C Up to 30 days
  • Working solution
    2–8°C Use within 7 days

Product specifications

Technical details

Technical specifications
CAS number
77591-33-4
Molecular formula
C212H350N56O78S
Molecular weight
4963.44 g/mol g/mol
Type
Peptide
Residues / units
43 amino acids
Vial size
3mL
Molecular weight
4963.44 g/mol — Registry verified

Storage & Handling

Storage conditions for unopened vials

LYOPHILIZED
-20°C

Long-term storage. Protect from moisture and light.

RECONSTITUTED
2–8°C

Refrigerate after reconstitution. Do not freeze reconstituted solution unless validated for your protocol.

SHIPPING
Ambient

Lyophilized peptides ship at ambient temperature under normal conditions.

WARNINGS
  • For research use only — not for human or veterinary consumption.
  • Handle with appropriate PPE in a controlled laboratory environment.
  • Confirm form, salt, and concentration against your supplier CoA before use.

Sources & References

Peer-reviewed research

TB-500 is a synthetic peptide derived from the active region of thymosin beta-4, a naturally occurring actin-binding protein involved in cellular migration and tissue organization. It has been studied extensively in regenerative research for its relationship to connective tissue signaling, angiogenesis, wound modeling, and cellular repair pathways across musculoskeletal and soft-tissue systems. Its sequence retains the biologically active region associated with actin regulation while functioning independently from the full thymosin beta-4 protein structure. Lyophilized powder, 3mL vial. Sold at 10mg per vial. For research use only.

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